HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Formylbenzonitrile → [3-(Aminomethyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Formylbenzonitrile | HCID 90670 | — |
| Reactant | [3,5-Bis(benzyloxy)benzyl]amine hydrochloride | HCID 15505554 | — |
| Product | [3-(Aminomethyl)phenyl]methanol | HCID 21880609 | 66% |
Reaction Steps
This compound was prepared by reduction of 3-cyanobenzaldehyde according to the procedure described in preparation of 3,5-dibenzyloxybenzylamine. Yield was 66%: 1H NMR (Acetone-d6, 500 MHz) δ7.32 (s, 1H), 7.23 (dd, 1H, J=7.6 and 7.0), 7.19, complex, 2H), 4.59 (s, 2H), 4.40 (s, 2H), 4.10 (br, 1H), 1.96 (br, 1H), 1.88 (br, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129225B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-743e1ab5eee84685b08d24bb4df3cbed |
| Source note | uspto-grants-2006_10 |