Sodium Nitrite → HCID 21906157, compound

HRID 1246745Notes

Reaction equation

HRID 1246745 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)[C:3]=1[NH2:17].[N:18]([O-])=O.[Na+]>>[Cl:1][C:2]1[C:3]2[N:17]=[N:18][N:9]([CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1

Participants

3

Reactant 2

HCID 23668193Sodium NitriteHCID 86038949HCID 86038949, compound

Product 1

HCID 21906157HCID 21906157, compound

Procedure

A solution of 6-chloro-N4-pyridin-2-ylmethyl-pyrimidine-2,4,5-triamine was treated with a cold aqueous solution of NaNO2, following the general procedure 2. 1HNMR (CDCl3): δ 8.60–8.59 (m, 1H), 7.71–7.67(m, 1H), 7.29–7.25 (m, 1H), 7.22–7.20 (m, 1H), 5.81 (s, 2H), 5.48 (s, 2H).

Sources & evidence

ORD record
ord-d0d4168a23cb47a99de7fbfc3779704b
Source dataset
uspto-grants-2006_10
Patent number
US07129244B2

Reaction notes

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