4-Chloroaniline → HCID 21905766, compound

Participants

Reaction Steps

4,6-Dichloro-2-methylpyrimidin-5-ylamine (100 mg, 0.56 mmol) and 4-chlorophenylamine (86 mg, 0.68 mmol) were combined in H2O (1.5 ml) and 10:1 ethanol/HCl (0.24 ml) and heated to reflux for 6 hours. The reaction mixture was cooled and H2O added to it. The product was collected by filtration and dried on high vacuum to give the desired compound I-(7A-80)a as a tan solid (173 mg) that was carried on crude: +ESI MS (M+1) 269.2.

Provenance & Evidence