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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1246869Generated: October 30, 2026

Nipecotic Acid → HCID 10118637, compound

https://huagongshe.com/reaction/1246869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNipecotic AcidHCID 4498—
Reactant4-HydroxypyrrolidineHCID 98210—
Reactant4-(4-(2,3-Dihydro-benzo(1,4)dioxin-6-ylsulfanyl)-3-trifluoromethyl-phenyl)-pyridineHCID 86585867—
ProductHCID 10118637HCID 10118637—

Reaction Steps

The title compound was prepared according to the procedures of Example 38E, substituting compound 76 with compound 118 (0.033 g, 0.0779 mmol) and 3-hydroxypyrrolidine with nipecotic acid. A yellow solid 128 was obtained (0.034 g, 66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129247B2
Source datasetuspto-grants-2006_10
ORD IDord-cc2518cab6c741c3865a1c449d002711
Source noteuspto-grants-2006_10