HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylhydrazine hydrochloride → 8-[2-(4-fluorophenyl)hydrazinyl]pyrrolo[2,3-g][1,3]benzothiazol-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylhydrazine hydrochloride | HCID 69981 | — |
| Reactant | 6H-thiazolo[5,4-e]indole-7,8-dione | HCID 11745756 | — |
| Product | 8-[2-(4-fluorophenyl)hydrazinyl]pyrrolo[2,3-g][1,3]benzothiazol-7-one | HCID 178517008 | 49% |
Reaction Steps
Prepared according to Example 96 with 6H-1-thia-3,6-diaza-as-indacen-7,8-dione (Procedure A) and 4-fluorophenylhydrazine hydrochloride in 49% yield. 1H NMR (DMSO-d6): δ 7.11 (d, J=8.6 Hz, 1H); 7.25 (t, J=8.8 Hz, 2H); 7.52 (dd, J=4.8, 8.8 Hz, 2H); 7.94 (d, J=8.6 Hz, 1H); 9.27 (s, 1H); 11.2 (s, 1H); 12.6 (s, 1H). ES-MS m/z 311 (M−1)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129253B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-9113c1a294e44510a622885aea6685e7 |
| Source note | uspto-grants-2006_10 |