HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 3420496, compound → N-(5-chloropyridin-2-yl)-2-hydroxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 3420496 | HCID 3420496 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | N-(5-chloropyridin-2-yl)-2-hydroxybenzamide | HCID 8033597 | 63.5% |
Reaction Steps
2-Acetoxy-N-(5-chloropyridin-2-yl)benzamide (1.45 g, 5 mmol) was saponified in aqueous methanolic NaOH. Standard acid-base workup gave 1.06 g of crude crystalline product which was recrystallized from acetone to give N-(5-chloropyridin-2-yl)-2-hydroxybenzamide (0.79 g, 63% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129245B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-5771e195884e44fc9b323503bacb3ff1 |
| Source note | uspto-grants-2006_10 |