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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247066Generated: October 30, 2026

Hydrochloric Acid → HCID 21906480, compound

https://huagongshe.com/reaction/1247066

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-MethylcyclohexanoneHCID 11419—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 21906397HCID 21906397—
ProductHCID 21906480HCID 21906480157.5%

Reaction Steps

Using a similar procedure to that described in Example 9-C, N-(5-chloropyridin-2-yl)-2-[(pyrrolidin-3-yloxycarbonyl)amino]benzamide trifluoroacetate (100 mg, 0.211 mmol), 2-methylcyclohexanone (0.12 mL, 1.05 mmol), and sodium cyanoborohydride (53 mg, 0.84 mmol) yielded, after treatment with HCl, 82 mg (80%) of the title compound as the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129245B2
Source datasetuspto-grants-2006_10
ORD IDord-da046e32471b4d549117a2c11c3f1701
Source noteuspto-grants-2006_10