Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247235Generated: October 31, 2026

4-(Aminomethyl)benzonitrile → (S)-N-(4-cyano-benzyl)-2-methoxy-2-phenyl-acetamide

https://huagongshe.com/reaction/1247235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
Reactant(+)-Methoxyphenylacetic acidHCID 643325—
Product(S)-N-(4-cyano-benzyl)-2-methoxy-2-phenyl-acetamideHCID 69290213—

Reaction Steps

(S)-(+)-Methoxyphenylacetic acid was coupled with 4-aminomethyl benzonitrile (CAS No: 10406-25-4) according to general procedure C to give (S)-N-(4-cyano-benzyl)-2-methoxy-2-phenyl-acetamide as an off-white solid. MS 281.2 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-5c5a5257c5344b73a5ee7f84c0f0ef61
Source noteuspto-grants-2006_10