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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247272Generated: October 26, 2026

4-(Aminomethyl)-3-fluorobenzonitrile → HCID 21905701, compound

https://huagongshe.com/reaction/1247272

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)-3-fluorobenzonitrileHCID 21905443—
Reactant(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acidHCID 67373142—
ProductHCID 21905701HCID 21905701—

Reaction Steps

(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid (example 15.1) was coupled with 4-aminomethyl-3-fluoro-benzonitrile according to general procedure B to give (RS)-N-(4-cyano-2-fluoro-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide. Yellow oil. MS 347.3 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-c4db54b73cf84257909fd503c543c6d8
Source noteuspto-grants-2006_10