反应详情

4-Bromo-2-fluorobenzaldehyde was reacted according to general procedure A using ethanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-2-(4-bromo-2-fluoro-phenyl)-N-(4-cyano-benzyl)-2-ethoxy-acetamide. Light yellow oil. MS 391.1 ([M+H]+)