HuagongsheHuagongshe Chemistry Print Report · For research reference only
(RS)-N-(4-cyano-benzyl)-2-(4-hydroxy-phenyl)-2-methoxy-acetamide → HCID 21905400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (RS)-N-(4-cyano-benzyl)-2-(4-hydroxy-phenyl)-2-methoxy-acetamide | HCID 21905457 | — |
| Reactant | HCID 86593041 | HCID 86593041 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21905400 | HCID 21905400 | — |
Reaction Steps
In analogy to example 16.4, (RS)-N-(4-cyano-benzyl)-2-(4-hydroxy-phenyl)-2-methoxy-acetamide (example 21.2) was alkylated with bromoethanol/cesium carbonate in DMF to give (RS)-N-(4-cyano-benzyl)-2-[4-(2-hydroxy-ethoxy)-phenyl]-2-methoxy-acetamide as a colorless oil. MS 363.1 ([M+Na]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-c5a63ed4948543ed989377c7cbb4936d |
| Source note | uspto-grants-2006_10 |