Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247295Generated: November 2, 2026

4-(Aminomethyl)benzonitrile → HCID 21905177, compound

https://huagongshe.com/reaction/1247295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Aminomethyl)benzonitrileHCID 82608—
Reactant4-[3-(Dimethylamino)propoxy]benzaldehydeHCID 546932—
ReactantDioxane MethanolHCID 21966525—
ProductHCID 21905177HCID 21905177—

Reaction Steps

4-[3-(Dimethylamino)propoxy]benzaldehyde was reacted according to general procedure A using methanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-[4-(3-dimethylamino-propoxy)-phenyl]-2-methoxy-acetamide. Colorless solid. MS 382.3 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-3bbbe8f04f8645729d4663e0f39137cb
Source noteuspto-grants-2006_10