HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Aminomethyl)benzonitrile → (RS)-N-(4-cyano-benzyl)-2-ethoxy-2-(2-fluoro-4-methoxy-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Aminomethyl)benzonitrile | HCID 82608 | — |
| Reactant | (RS)-Ethoxy-(2-fluoro-4-methoxy-phenyl)-acetic acid | HCID 21904991 | — |
| Product | (RS)-N-(4-cyano-benzyl)-2-ethoxy-2-(2-fluoro-4-methoxy-phenyl)-acetamide | HCID 21904995 | — |
Reaction Steps
(RS)-Ethoxy-(2-fluoro-4-methoxy-phenyl)-acetic acid was coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-ethoxy-2-(2-fluoro-4-methoxy-phenyl)-acetamide. Yellow oil. MS 343.2 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-f7c4af0c93cc4598a82669feba7a8c3c |
| Source note | uspto-grants-2006_10 |