HCID 69291892, compound → HCID 45115839, compound

HRID 1247310Notes

Reaction equation

HRID 1247310 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH:15]([O:19][CH3:20])[C:16]([OH:18])=[O:17])=[C:11]([F:21])[CH:10]=1)C1C=CC=CC=1>[Pd].CCO>[F:21][C:11]1[CH:10]=[C:9]([OH:8])[CH:14]=[CH:13][C:12]=1[CH:15]([O:19][CH3:20])[C:16]([OH:18])=[O:17]

Participants

4

Reactant 1

HCID 69291892HCID 69291892, compound

Product 1

HCID 45115839HCID 45115839, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

(RS)-(4-Benzyloxy-2-fluoro-phenyl)-methoxy-acetic acid was hydrogenated at rt and normal pressure using 10% Pd/C as a catalyst and EtOH as a solvent to give (RS)-(2-fluoro-4-hydroxy-phenyl)-methoxy-acetic acid as a light yellow oil. MS 199.2 ([M−H]−)

Workup

  1. customwas hydrogenated at rt

Sources & evidence

ORD record
ord-09d97d020e6c4d8a8b3ece4801a9a250
Source dataset
uspto-grants-2006_10
Patent number
US07129238B2

Reaction notes

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