HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → HCID 21905014, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 21905330 | HCID 21905330 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21905014 | HCID 21905014 | — |
Reaction Steps
In analogy to example 16.4, (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-hydroxy-phenyl)-2-methoxy-acetamide was alkylated with 2-iodopropane and cesium carbonate in DMF to give (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-isopropoxy-phenyl)-2-methoxy-acetamide. Light yellow oil. MS 357.2 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-622c6321f19941ebb9a2ebd20dc212c2 |
| Source note | uspto-grants-2006_10 |