HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyl iodide → HCID 21905248, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyl iodide | HCID 10556 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 21905330 | HCID 21905330 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21905248 | HCID 21905248 | — |
Reaction Steps
In analogy to example 16.4, (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-hydroxy-phenyl)-2-methoxy-acetamide (example 70.4) was alkylated with 1-iodo-2-methylpropane and cesium carbonate in DMF to give (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-isobutoxy-phenyl)-2-methoxy-acetamide. Off-white, amorphous solid. MS 371.3 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-375b29418d2d474591810e4cccc7c361 |
| Source note | uspto-grants-2006_10 |