HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 21905088, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | HCID 21905042 | HCID 21905042 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21905088 | HCID 21905088 | — |
Reaction Steps
In analogy to example 16.4 (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-6-hydroxy-phenyl)-2-methoxy-acetamide (example 80.4) was reacted with 2-bromoethanol in the presence of cesium carbonat in DMF to give N-(4-cyano-benzyl)-2-[2-fluoro-6-(2-hydroxy-ethoxy)-phenyl]-2-methoxy-acetamide. White solid. MS 359.2([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07129238B2 |
| Source dataset | uspto-grants-2006_10 |
| ORD ID | ord-5d3ffed2eae044aa9208b59c3ab3d501 |
| Source note | uspto-grants-2006_10 |