反应详情

(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid, described in example 15.1 was coupled with 4-aminomethyl-3-chlorobenzonitrile (CAS 202521-97-9) according to general procedure B to give (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide. Light green solid. MS 361.1 ([M−H]−)