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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247344Generated: November 2, 2026

4-(AMINOMETHYL)-3-METHOXYBENZONITRILE → HCID 21904851, compound

https://huagongshe.com/reaction/1247344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(AMINOMETHYL)-3-METHOXYBENZONITRILEHCID 18424090—
Reactant(RS)-Ethoxy-(2-fluoro-4-methoxy-phenyl)-acetic acidHCID 21904991—
ProductHCID 21904851HCID 21904851—

Reaction Steps

(RS)-Ethoxy-(2-fluoro-4-methoxy-phenyl)-acetic acid, described in example 63.1 was coupled with 4-aminomethyl-3-methoxy-benzonitrile (CAS 182159-14-4) according to general procedure B to give (RS)-N-(4-cyano-2-methoxy-benzyl)-2-ethoxy-2-(2-fluoro-4-methoxy-phenyl)-acetamide. Yellow oil. MS 373.2 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129238B2
Source datasetuspto-grants-2006_10
ORD IDord-83590eb24ef645c099b889daad2d5e9c
Source noteuspto-grants-2006_10