反应详情

The crude 4-bromo-2,6-difluorobenzaldehyde described in example 69.1 was reacted according to general procedure A using ethanol/dioxane as a solvent. The product of this reaction was subsequently coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-2-(4-bromo-2,6-difluoro-phenyl)-N-(4-cyano-benzyl)-2-ethoxy-acetamide. Yellow oil.

1. customwas reacted