(2-Hydroxyphenyl)boronic acid → HCID 21905739, compound

Participants

Reaction Steps

In analogy to example 247.1, (RS)-2-(4-bromo-2,6-difluoro-phenyl)-N-(4-cyano-benzyl)-2-ethoxy-acetamide (example 248.1) was reacted with 2-hydroxyphenylboronic acid to give (RS)-N-(4-cyano-benzyl)-2-(3,5-difluoro-2′-hydroxy-biphenyl-4-yl)-2-ethoxy-acetamide. Off-white solid. MS 423.0 ([M+H]+)

Provenance & Evidence