HCID 21907550, compound → HCID 21907514, compound

Participants

Reaction Steps

A solution of tert-butyl 4-(6-nitro-1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenylcarbamate (0.276 g, prepared by substituting Example 128B for Example 1A in Examples 1B and 1C) in TFA (3 mL) and CH2Cl2 (3 mL) was stirred at room temperature for 1 hour, then concentrated to give 0.085 g of the desired product. 1H NMR (300 MHz, DMSO-d6) δ 4.66 (s, 2H), 5.50 (s, 2H), 6.70 (d, J=8.5 Hz, 1H), 7.40 (d, J=8.8 Hz, 2H), 8.20 (d, J=2.0 Hz, 1H), 8.30 (d, J=2.0 Hz, 1H), 9.03 (s, 1H).

Provenance & Evidence