2-Chloroethyl methyl sulfide → 3-amino-1-[2-(methylthio)ethyl]-3,4-dihydroquinolin-2(1H)-one

Participants

Role	Name	HCID	Charge
Reactant	2-Chloroethyl methyl sulfide	HCID 10965	—
Reactant	2-Chloro-N-[1-(2,2-dimethyl-1,3-dioxolan-4(R)-ylmethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3(R,S)-yl]-6H-thieno[2,3-b]pyrrole-5-carboxamide	HCID 10389501	—
Product	3-amino-1-[2-(methylthio)ethyl]-3,4-dihydroquinolin-2(1H)-one	HCID 21906828	—

Reaction Steps

Prepared by an analogous method to 3-amino-1-(2-methoxyethyl)-3,4-dihydroquinolin-2(1H)-one (Method 12) using 2-chloroethyl methyl sulphide instead of 2-bromoethyl methyl ether to give the title product as a clear, brown gum.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07129249B2
Source dataset	uspto-grants-2006_10
ORD ID	ord-50f711212f2140c6b5922d20366d1fec
Source note	uspto-grants-2006_10