Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1247630Generated: November 3, 2026

2-Chloroethanol → 2-(Pyridin-3-yloxy)ethan-1-ol

https://huagongshe.com/reaction/1247630

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroethanolHCID 34—
Reactant3-HydroxypyridineHCID 7971—
ReactantPotassium CarbonateHCID 11430—
SolventDimethylformamideHCID 6228—
Product2-(Pyridin-3-yloxy)ethan-1-olHCID 21908997—

Reaction Steps

The yield of the title compound according to D1, starting from 3-hydroxypyridine, 2-chloroethanol and K2CO3 in DMF was 19%. The title compound has also been prepared according to EP 0 286 242 A2 starting from methyl [(3-pyridinyl)oxy]acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07129354B2
Source datasetuspto-grants-2006_10
ORD IDord-0b884f2490fe4dca89e63f881e656adb
Source noteuspto-grants-2006_10