Ethyl bromoacetate → Acetic acid, [[5′-(acetyloxy)[1,1′:3′,1′′-terphenyl]-2′-yl]oxy]-, ethyl ester

Participants

Reaction Steps

A mixture of 4acetoxy-2,6diphenylphenol (6.1 g, 20 mmol; prepared as described in Ber. 101, 2519 (1968)), ethyl bromoacetate )4.0 g, 24 mmol), potassium carbonate (3.3 g, 24 mmol) and 2-butanone (150 ml) was refluxed for 24 h, then filtered and the solvent evaporated. The residue was purified by chromatography on silica gel) 120 g, eluent benzene) to give 7.2 g (92%) of oily ethyl 4-acetoxy-2,6-diphenylphenoxyacetate.

Provenance & Evidence