反应详情

A solution of {4-[3,3-bis-(2-furanyl)-allylsulfanyl]-2-trifluoromethyl-phenoxy}-acetic acid ethyl ester (35 mg, 0.077 mmol) in 1N NaOH (0.1 ml) and ethanol (5 ml) was stirred at room temperature for 2 hours. The reaxtion mixture was evaporated and the residue dissolved in 1 N HCl (0.15 ml). The aquous phase was extracted with methylene choride (3×25 ml), dried (MgSO4) and evaporated to give the title compound in 30 mg (92%) yield.

1. customThe reaxtion mixture was evaporated
2. dissolutionthe residue dissolved in 1 N HCl (0.15 ml)
3. extractionThe aquous phase was extracted with methylene choride (3×25 ml)
4. dry with materialdried (MgSO4)
5. customevaporated