Sulfuric Acid → HCID 69462687, compound

Participants

Reaction Steps

To a solution of 1-(2-fluoroethyl)-4-nitroso-1H-pyrazol-5-amine (4.8 g) in water (30 ml) and methanol (30 ml) were added sulfuric acid (2.98 g) and 10% palladium on carbon (2.5 g), and the mixture was hydrogenated under balloon pressure for 7.5 hours. The reaction mixture was filtered through a bed of Celite, and the filtrate was concentrated in vacuo. 2-Propanol was added to the residue, and the precipitate was collected by filtration to give 1-(2-fluoroethyl)-1H-pyrazole-4,5-diamine sulfate (7 g).

Provenance & Evidence