1-Butanol → HCID 13476025, compound

HRID 1247949Notes

Reaction equation

HRID 1247949 reaction equation
[NH2:1][C:2]1[C:6]([C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[O:8])=[CH:5][NH:4][N:3]=1.[CH2:15](O)[CH2:16][CH2:17][CH3:18]>>[CH3:18][C:17]1[CH:16]=[C:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]2[N:4]=[CH:5][C:6]([C:7]([C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=3)=[O:8])=[C:2]2[N:1]=1

Participants

3

Reactant 2

HCID 2631-ButanolHCID 178509267HCID 178509267, compound

Product 1

HCID 13476025HCID 13476025, compound

Procedure

A mixture of 0.01 mole of 1-(3-phenyl)butan-1,3-dione and 0.01 mole of (3-amino-1H-pyrazol-4-yl)phenyl-methanone in 25 ml of n-butanol was refluxed for 8 hours. The solvent was removed and the product isolated as described in Example 1, giving the desired product as crystals, mp 165°-166° C.

Workup

  1. temperaturewas refluxed for 8 hours
  2. customThe solvent was removed
  3. customthe product isolated

Sources & evidence

ORD record
ord-2b56d334c0444f3c85ae59c5dc7334ef
Source dataset
uspto-grants-1985_06
Patent number
US04521422

Reaction notes

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