HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 3-Ethoxy-1-(3-pyridinyl)-2-propen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one | HCID 567033 | — |
| Product | 3-Ethoxy-1-(3-pyridinyl)-2-propen-1-one | HCID 54032326 | — |
Reaction Steps
A mixture of 0.10 mole of 3-dimethylamino-1-(3-pyridinyl)-2-propen-1-one and 0.20 mole of p-toluenesulfonic acid in 150 ml of anhydrous ethanol was refluxed for 10 hours. The solvent was removed and the residue partitioned between water and dichloromethane. The organic layer was dried over magnesium sulfate and the solvent removed, giving 3-ethoxy-1-(3-pyridinyl)-2-propen-1-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04521422 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-64c5b816faa34d3e82a72f8bd2cc1385 |
| Source note | uspto-grants-1985_06 |