2-Propen-1-one, 3-(dimethylamino)-1-(4-pyridinyl)- → HCID 13475997, compound

HRID 1247962Notes

Reaction equation

HRID 1247962 reaction equation
[NH2:1][C:2]1[C:6]([C:7]([C:9]2[S:10][CH:11]=[CH:12][N:13]=2)=[O:8])=[CH:5][NH:4][N:3]=1.CN(C)[CH:16]=[CH:17][C:18]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=O>>[N:23]1[CH:24]=[CH:25][C:20]([C:18]2[N:3]3[N:4]=[CH:5][C:6]([C:7]([C:9]4[S:10][CH:11]=[CH:12][N:13]=4)=[O:8])=[C:2]3[N:1]=[CH:16][CH:17]=2)=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 7145312-Propen-1-one, 3-(dimethylamino)-1-(4-pyridinyl)-HCID 178509270HCID 178509270, compound

Product 1

HCID 13475997HCID 13475997, compound

Procedure

As described for Example 1, (3-amino-1H-pyrazol-4-yl)-2-thiazolyl-methanone was reacted with 3-dimethylamino-1-(4-pyridinyl)-2-propen-1-one to give the product as crystals, mp 323°-325° C.

Sources & evidence

ORD record
ord-8d97dcb8397949a2bf10cd3207b38d55
Source dataset
uspto-grants-1985_06
Patent number
US04521422

Reaction notes

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