Dichloromethane → HCID 13476004, compound

Participants

Reaction Steps

A solution of 1.77 g of 3-amino-4-furanylpyrazole and 2.32 g of N-[3-[3-(dimethylamino)-1-oxo-2-propenyl]phenyl]acetamide (Example 168) in 50 ml of glacial acetic acid was refluxed for 10 hours. Evaporation of the reaction mixture gave a solid which was treated with a saturated sodium bicarbonate solution and 200 ml of methylene chloride. The solid that precipitated was recovered by filtration and proved to be the desired product (2.57 g, mp 195°-196° C.). An additional quantity of product was isolated from the methylene chloride solution, mp 195°-196° C.

Provenance & Evidence