HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-oxovalerate → HCID 20278411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-oxovalerate | HCID 121699 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 2-{4-[4-(Trifluoromethyl)phenoxy]phenoxy}propanoyl chloride | HCID 12906015 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 20278411 | HCID 20278411 | — |
Reaction Steps
Following the procedure of Example 1, 2-[4-(4-trifluoromethylphenoxy)phenoxy]propionic acid chloride is added to the sodium salt of methyl propionylacetate in benzene to give methyl 2-propionyl-4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-oxopentanoate (cpd. 16 in Table A). This pentanoate is then heated with DMSO and NaCl to give 2-[4-(4-trifluoromethylphenoxy)phenoxy]-3,5-heptanedione (cpd. 16, Table B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04522647 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-7a4abe79b7704f0198cde231e11d303e |
| Source note | uspto-grants-1985_06 |