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HRID1248109

反应详情

EQUATION

反应方程式

HRID 1248109 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(N)Cc1c[nH]c2ccc(Br)cc12
HCID13259

Indole, 3-(2-amino-2-methylpropyl)-5-bromo-

C12H15BrN2

结构：N#C[Cu]C#N
HCID178418260

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(N)Cc1c[nH]c2ccc(C#N)cc12
HCID14044134

3-(2-Amino-2-methylpropyl)-1H-indole-5-carbonitrile

C13H15N3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN1CCCC1=O
溶剂HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

PROCEDURE

实验过程

A mixture of 6.45 g of 2-(5-bromo 3-indolyl)1,1-dimethyl ethylamine and 3.25 g of copper cyanide in 40 ml of N-methylpyrrolidone is heated to reflux for 5 hours.

WORKUP

后处理

  1. temperatureis heated
  2. temperatureto reflux for 5 hours