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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1248159Generated: October 31, 2026

Formaldehyde → 3-(3-tert-Butyl-1,3-oxazolidin-5-yl)phenol

https://huagongshe.com/reaction/1248159

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 54151805HCID 54151805—
Product3-(3-tert-Butyl-1,3-oxazolidin-5-yl)phenolHCID 20134478—

Reaction Steps

In the manner described in Example 32, m-(benzyloxy)-α-[(tert-butylamino)methyl]benzyl alcohol is reacted with formaldehyde to afford the oxazolidine derivative, which is debenzylated by the procedure of Example 28 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04522822
Source datasetuspto-grants-1985_06
ORD IDord-4a3980b9e18d4de9ba139e3e45329273
Source noteuspto-grants-1985_06