Acetonitrile → HCID 70485151, compound

Participants

Reaction Steps

The title compound of Example 4 (1.5 g, 4.8 mmole) was stirred in 60 ml of acetonitrile containing 2.3 ml (ca. 24 mmole) of acetic anhydride. After 18 hours the reaction mixture was concentrated to dryness in vacuo and the residue was dissolved in water. The solution was then made alkaline with aqueous sodium bicarbonate and extracted with dichloromethane. After the organic phase was dried over magnesium sulfate, filtered, and concentrated in vacuo, the residue was recrystallized from diethyl ether to give 398 mg of the title compound. Structure assignment was supported by nmr spectrum and by elemental analysis.

Provenance & Evidence