Ethyl 3-(6-methylpyridin-3-yl)prop-2-enoate → Ethyl 3-(6-methyl-3-pyridyl)propionate

HRID 1248288Notes

Reaction equation

HRID 1248288 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1>C(O)C.[Pd]>[CH3:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 54365744Ethyl 3-(6-methylpyridin-3-yl)prop-2-enoate

Product 1

HCID 3018102Ethyl 3-(6-methyl-3-pyridyl)propionate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl 3-(6-methyl-3-pyridyl)acrylate (60.36 g) was hydrogenated in ethanol at 35° and 355 kPa using palladium-on charcoal catalyst (10%, 1.0 g). The mixture was filtered and the filtrate was evaporated to give ethyl 3-(6-methyl-3-pyridyl)propionate as an oil.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-51c605098fd74279b888f744c9fb481c
Source dataset
uspto-grants-1985_06
Patent number
US04523015

Reaction notes

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