HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → 2-Nitroamino-5-(2-methoxy-4-pyridyl)-4-pyrimidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Ethyl 2-formyl-3-(2-methoxy-4-pyridyl)propionate | HCID 21273312 | — |
| Reactant | Nitroguanidine | HCID 86287517 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Nitroamino-5-(2-methoxy-4-pyridyl)-4-pyrimidone | HCID 20279276 | — |
Reaction Steps
By a process similar to that of Example 5, reaction of nitroguanidine, sodium methoxide and ethyl 2-formyl-3-(2-methoxy-4-pyridyl)-propionate gave 2-nitroamino-5-(2-methoxy-4-pyridyl)-4-pyrimidone, m.p. 194°-5.5° (from aqueous acetic acid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04523015 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-05a0c07d3e0d4d1cbb404ea2031c6c25 |
| Source note | uspto-grants-1985_06 |