Piperonyl Butoxide → gamma-Cyclodextrin piperonyl butoxide

Participants

Reaction Steps

1.5 g (1.16 millimoles) of γ-cyclodextrin are dissolved in 10 ml of distilled water at room temperature whereupon a solution of 0.5 ml (0.53 g, 1.56 millimoles) of piperonyl butoxide in 10 ml of 96% by Vol. ethanol is added. One proceeds furtheron as described in Example 1. Thus 1.32 g of an inclusion complex of γ-cyclodextrin and piperonyl butoxide are obtained. The piperonyl butoxide content of the complex amounts to 26.5% which corresponds to a molar ratio of 1.38 moles of PBO/1 moles of γ-cyclodextrin. The solubility of the complex is 0.165 mg/ml, at 20° C., as measured by shaking for an hour.

Provenance & Evidence