Piperonyl Butoxide → beta-Cyclodextrin piperonyl butoxide

Beteiligte Stoffe

Reaktionsschritte

20 g (17.62 millimoles) of β-cyclodextrin and 5 ml (5.3 g, 15.6 millimoles) of piperonyl butoxide are homogenized in a pug mill under intensive kneading, whereupon the mixture is dried in a vacuum exsiccator over phosphorous pentoxide. Thus 25.1 g of an β-cyclodextrin-piperonyl butoxide inclusion complex are obtained. The product is a white crystalline not moist substance which is a little oily to the touch. The piperonyl butoxide content of the complex amounts to 20% which corresponds to a molar ratio of 0.84 mole of PBO/1 mole of β-cyclodextrin. The solubility of the complex amounts to 0.165 mg/ml, at 20° C., measured by shaking for an hour.

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