Methyl iodide → HCID 13330684, compound

Participants

Reaction Steps

Methyl iodide (2.74 g) was added to a stirred solution of 5-butyl-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone (3.5 g) and sodium hydroxide (0.78 g) in water (10 ml) and ethanol (20 ml) at room temperature and heated at 70° for 45 minutes. The solid which separated on standing was filtered and washed with ethanol and water to give the title compound (0.95 g) m.p. 138°-140.5°.

Provenance & Evidence