Triethylamine → HCID 20277905, compound

Participants

Reaction Steps

N-Benzyl-3-bromopropanamide (6 g), methallylamine (1.9 g) and triethylamine (3.5 ml) in dimethylformamide (12 ml) were heated together under reflux for 21/4 hr, then poured into ethyl actate (100 ml). The organic phase was washed with water (2×100 ml), saturated brine (100 ml) and dried over magnesium sulphate. Removal of the solvent under reduced pressure gave a yellow oil which produced the title compound in 17% yield after column chromatography using ethyl acetate:ethanol (1:1) as eluent.

Provenance & Evidence