Formaldehyde → HCID 20487215, compound

Participants

Reaction Steps

Into a one-gallon autoclave 338 g (4.5 mole) glycine, 1 liter H2O, 10 g 10% Pd/C, and 500 g methylethylketone were combined and hydrogenated as in Example 7. At 110° C., 52.7 kg/cm2 of hydrogen was consumed in 3.5 hours. After cooling 365 g of 37% (4.5 moles) aqueous formaldehyde was added. The hydrogen pressure was maintained between 63.3 and 77.3 kg/cm2 while heating and 52.7 kg/cm2 hydrogen was consumed below 65° C. within about 1.5 hours. The resulting solution was filtered and concentrated on a hot plate to about 1200 ml. 1272 g of a solution containing 52.7% solids (theory 51.3% solids) was obtained.

Provenance & Evidence