HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,5-Trimethylphenol → Ethyl 6-(2'-hydroxy-3',4',6'-trimethylbenzoyl)hexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,5-Trimethylphenol | HCID 12769 | — |
| Reactant | Ethyl 6-(Chloroformyl)hexanoate | HCID 543232 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | Ethyl 6-(2'-hydroxy-3',4',6'-trimethylbenzoyl)hexanoate | HCID 12906130 | — |
Reaction Steps
2,3,5-Trimethylphenol (formula VII wherein R=H3C, X=H, Y=OH)(0.9 part), aluminum chloride (2.1 parts) and ethyl 6-chloroformylhexanoate (1.3 part) were treated as in Example 1 (1). The procedure provided colorless needles of ethyl 6-(2'-hydroxy-3',4',6'-trimethylbenzoyl)hexanoate (formula II-1 wherein R=H3C, X=H, Y=OH, n=5, in the form of ethyl ester) (1.5 part) melting at 47°-48° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04525361 |
| Source dataset | uspto-grants-1985_06 |
| ORD ID | ord-a21b7f6407f340d2996763c87655e032 |
| Source note | uspto-grants-1985_06 |