Succinic Acid → HCID 20277158, compound

Participants

Reaction Steps

A solution of 1-[2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl]imidazole (0.8 g, 3.67 mmol) in hot ethanol (10 ml) was added to a solution of succinic acid (0.4 g, 3.39 mmol) in hot ethanol. After boiling for 0.15 h, the reaction mixture was concentrated to afford a colourless oil which solidified on trituration with ethyl acetate/petroleum ether (b.p. 40°-60°) to a white solid. Recrystallisation of the solid from ethyl acetate/petroleum ether (b.p. 40°-60°) afforded 1-[2-(6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl]imidazole hydrogen succinate, m.p.

Provenance & Evidence