Aluminum(III) Chloride → HCID 5134352, compound

HRID 1248784Notes

Reaction equation

HRID 1248784 reaction equation
[Al+3].[Cl-].[Cl-].[Cl-].[CH2:5]([CH:9]1[CH2:14][CH2:13][CH:12]([C:15](Cl)=[O:16])[CH2:11][CH2:10]1)[CH2:6][CH2:7][CH3:8]>C1C=CC=CC=1>[C:15]([CH:12]1[CH2:13][CH2:14][CH:9]([CH2:5][CH2:6][CH2:7][CH3:8])[CH2:10][CH2:11]1)(=[O:16])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 6451240Aluminum(III) ChlorideHCID 13531120HCID 13531120, compound

Product 1

HCID 5134352HCID 5134352, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Conditions

Temperature
40 °C

Procedure

To a stirred mixture of 500 ml abs. benzene and 240 g (1.8 mol) AlCl3 at 20° C., within 60 minutes, are added, dropwise, 302 g (1.5 mol) of 4-n-butyl-cyclohexanecarboxylic acid chloride (cis-trans mixture). The clear orange-yellow solution is then heated to 40° C. for 1 to 2 hours, cooled and poured onto 500 ml ice/concentrated HCl. The organic phase is separated, washed with water, with 10% aqueous potassium hydroxide solution and washed with water again. The aqueous phase is extracted two to three times with benzene or ether. The combined organic extracts are dried over Na2So4 and the solvent is removed in vacuum.

Workup

  1. additionTo a stirred mixture of 500 ml abs
  2. additionare added
  3. temperaturecooled
  4. customThe organic phase is separated
  5. washwashed with water, with 10% aqueous potassium hydroxide solution
  6. washwashed with water again
  7. extractionThe aqueous phase is extracted two to three times with benzene or ether
  8. customThe combined organic extracts are dried over Na2So4
  9. customthe solvent is removed in vacuum

Sources & evidence

ORD record
ord-16f97e7aceab4b97b872e136df30f0fe
Source dataset
uspto-grants-1986_12
Patent number
US04626375

Reaction notes

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