HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidone carboxylic acid → Amsacrine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidone carboxylic acid | HCID 499 | — |
| Reactant | m-AMSA L(+)-lactate | HCID 131714982 | — |
| Product | Amsacrine | HCID 2179 | — |
Reaction Steps
In the above formulations, a mixture of m-AMSA-L(+)-lactate and 1 mole equivalent of D,L-pyroglutamic acid will provide a 5 mg/ml m-AMSA solution which will not precipitate. The use of L-pyroglutamic acid in place of D,L-pyroglutamic acid will provide a 5 to 7.5 mg/ml solution which will not precipitate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04626541 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-0a1da1abd6fe41149c85380bf6a9739e |
| Source note | uspto-grants-1986_12 |