HCID 53797197, compound → HCID 13771287, compound
Reaction equation
[NH2:1][C:2]1[C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[CH:5][NH:4][N:3]=1.CN(C)[CH:14]=[CH:15][C:16]([C:18]1[CH:19]=[C:20]([NH:24][C:25]([CH:27]2[CH2:30][CH2:29][CH2:28]2)=[O:26])[CH:21]=[CH:22][CH:23]=1)=O>>[CH:27]1([C:25]([NH:24][C:20]2[CH:19]=[C:18]([C:16]3[N:3]4[N:4]=[CH:5][C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[C:2]4[N:1]=[CH:14][CH:15]=3)[CH:23]=[CH:22][CH:21]=2)=[O:26])[CH2:28][CH2:29][CH2:30]1Participants
3
Procedure
A 0.78 g portion of 3-amino-4-carboethoxypyrazole ard 1.36 g of N-[3-[3-(dimethylamino)-1-oxo-2-propenyl]phenyl]cyclobutanecarboxamide were reacted as described in Example 13, giving 1.52 g of the desired product, mp 123°-125° C.
Sources & evidence
- ORD record
- ord-98a1c193c851467a8a2de2c310206f9c
- Source dataset
- uspto-grants-1986_12
- Patent number
- US04626538
Reaction notes
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