Hexanal → HCID 20226085, compound

HRID 1248821Notes

Reaction equation

[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH:20](=[O:26])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>>[C:1]([O:5][C:6]([NH:8][C:9]1[S:13][N:12]=[C:11]([CH:14]([CH:20]([OH:26])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 6184Hexanal

HCID 20226075HCID 20226075, compound

Product 1

HCID 20226085HCID 20226085, compound

Procedure

1.0 g (3.5 mMol) of product from Example 28 were reacted with 1.26 ml (~10 mMol) of n-hexanal for 9 days in the manner described in Example 29. Yield of erythro/threo mixture of the title compound: 1.1 g (~80%).

Sources & evidence

ORD record: ord-fb15939026b44b4ea873bff52a4dc464
Source dataset: uspto-grants-1986_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04626535

Reaction notes

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