HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Bromoacetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid → 7-(1-Methylimidazole-2-ylthio)-acetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Bromoacetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid | HCID 14502350 | — |
| Reactant | HCID 178480602 | HCID 178480602 | — |
| Product | 7-(1-Methylimidazole-2-ylthio)-acetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid | HCID 131714985 | 60% |
Reaction Steps
1.0 g. of 7-bromoacetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid and 0.23 g. of 1-methyl-2-mercapto-imidazole were reacted and worked up according to Example 15. Thus 0.67 g. (60%) of 7-(1-methylimidazole-2-ylthio)-acetamido-3-(2,6-dichlorobenzoylamino)methylceph-3-em-4-carboxylic acid were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04626533 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-bac69fff52db41bfaf2b14340ad1ff95 |
| Source note | uspto-grants-1986_12 |