HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-anilinopyridine-3-carboxylate → 3-Butyl-4-hydroxy-1-[3-(methylsulfanyl)phenyl]-1,8-naphthyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-anilinopyridine-3-carboxylate | HCID 10998755 | — |
| Reactant | Methyl 2-[3-(methylsulfanyl)anilino]pyridine-3-carboxylate | HCID 13506724 | — |
| Reactant | Sch 12223 | HCID 54704755 | — |
| Product | 3-Butyl-4-hydroxy-1-[3-(methylsulfanyl)phenyl]-1,8-naphthyridin-2(1H)-one | HCID 54710249 | — |
Reaction Steps
Prepare the 3-(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridin-2(1H)one by the process of Example 1 by replacing the methyl 2-(3-methylthiophenylamino)-3-pyridine carboxylate with an equivalent amount of methyl 2-phenylamino-3-pyridine carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04628055 |
| Source dataset | uspto-grants-1986_12 |
| ORD ID | ord-564ed98fa66c4d2b99464f578864fd03 |
| Source note | uspto-grants-1986_12 |